It looks like one or the other, but not both can have a slight protective effect. Sano, M et al A controlled trial of selegline, apha-tocopherol, or both as treatment for Alzheimer's disease. New England Journal of Medicine, 336, 1216-1222, 1997. Latest results - Low plasma vitamin E concentrations contribute to a slightly higher risk of developing dementia later: Helmer C, Peuchant E, Letenneur L, Bourdel-Marchasson I, Larrieu S, Dartigues JF, Dubourg L, Thomas MJ, Barberger-Gateau P. Association between antioxidant nutritional indicators and the incidence of dementia: results from the PAQUID prospective cohort study. Eur J Clin Nutr. 57(12):1555-61, 2003.*   *Understanding references: The pharmacological agent being investigated is indicated in the title. Titles are followed by the Journal Name, the Volume, the Pages, and the Year (sometimes the year comes earlier in the sequence). Checking the most recent work by the same authors is one way to keep up to date. Another way is to look up articles in the Citation Index that cite this earlier article.

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